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1 March 2022Big PharmaMuireann Bolger

Ono sues AstraZeneca over antibody patents

Japan-based Ono Pharmaceuticals has sued AstraZeneca, accusing the US pharma company of infringing patents covering an antibody used in cancer treatment.

In a statement, Ono confirmed that it had filed the complaint at the Tokyo District Court on Monday, February 28.

The dispute concerns an anti-PD-L1 antibody that Ono argued is protected by the Japanese patent numbers, JP5885764 and JP6258428.

This antibody blocks programmed cell death 1 receptor (PD-1) and programmed cell death receptor ligand 1 (PD-L1) that are responsible for the development of cancers in some patients.

The lawsuit alleged that AstraZeneca infringed through the marketing, sale and distribution of Imfinzi (durvalumab).

Durvalumab is an FDA-approved immunotherapy for cancer, developed by Medimmune and AstraZeneca, and is known as a checkpoint inhibitor drug.

Commenting on its lawsuit, Ono said: “We recognise IP as an extremely important management asset. Therefore, we have decided to take appropriate measures against acts that infringe our IP rights, leading to the filing of such a lawsuit this time.”

It added that given the treatment is related to the life-saving of patients, that it would not ask for a sales injunction of Imfinzi if it struck a deal with AstraZeneca before the legal proceedings began.

The company said however it expected an appropriate compensation, including royalties.

LSIPR has approached AstraZeneca for comment.

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More on this story

Generics
8 February 2022   AstraZeneca and Merck, Sharp & Dohme have filed a pair of lawsuits against MSN and Sandoz, claiming their planned generic versions of its leukaemia treatment Calquence infringe six patents.
Americas
25 June 2019   Boston-based Dana-Farber Cancer Institute is seeking a share of the $1.6 billion in licensing revenue that BMS and Ono Pharmaceutical Co have allegedly received from six immunotherapy patents.